Members of Penningtons' North American Practice Group serve North American law firms and their clients wishing to do business in the UK and, through Penningtons' contacts with other member firms of the European Law Group, continental Europe. Members of the group maintain close links with firms and clients in the United States and Canada through contacts with North American law firms in London and with the American community in the UK.

Penningtons has experience in setting up businesses in the UK, banking and security transactions, US litigation involving UK parties as well as domestic litigation, real property acquisitions, intellectual property, UK and European competition law, mergers and acquisitions, employment, public issues of securities and tax planning and immigration.